At PromiseCare Medical Group in Hemet, California, liver health is a top priority. Since the liver works tirelessly behind the scenes to filter toxins and keep you alive, monitoring its function is crucial.

Liver Function Tests (LFTs) are a key diagnostic tool used by the medical team to gauge liver performance and detect potential issues. These tests measure enzymes, proteins, and byproducts in your blood, such as ALT, AST, and bilirubin, to assess liver inflammation, damage, or dysfunction.

Under the guidance of the medical professionals at PromiseCare Medical Group, patients can undergo LFTs to understand their liver’s health better and take steps to prevent or manage conditions like liver disease.

Overview

The liver plays a vital role in maintaining overall health, and liver function tests (LFTs) are essential in evaluating its performance. LFTs measure the levels of various enzymes, proteins, and byproducts in the blood, providing insight into the liver’s functioning.

These tests typically include measurements of alanine aminotransferase (ALT), aspartate aminotransferase (AST), bilirubin, albumin, and prothrombin time (PT). Elevated ALT and AST levels can indicate liver inflammation or damage, while abnormal bilirubin levels can signal liver dysfunction.

Albumin levels assess the liver’s ability to produce proteins, and prothrombin time evaluates its role in blood clotting. Abnormal liver function can indicate underlying liver diseases, making LFTs a crucial tool for screening and monitoring. Understanding test results can help individuals take control of their liver health.

Various factors can affect the liver’s performance, and LFTs can help identify potential issues. Healthcare providers can more effectively diagnose and treat liver-related conditions by analyzing the levels of different enzymes and proteins.

Understanding the significance of LFTs in maintaining liver health and addressing any abnormalities that may arise.

Types

Commonly, when undergoing liver function tests, a series of tests are performed to measure various aspects of the liver’s performance. These tests assess the liver’s health and function by measuring certain enzymes and protein levels in the blood.

Tests for liver enzymes such as alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP), and gamma-glutamyl transferase (GGT) are typically included. These enzymes are released into the bloodstream when liver cells are damaged.

Tests to evaluate the liver’s ability to process waste products, such as the bilirubin test, measure the levels of bilirubin in the blood. Additionally, tests assess the liver’s capacity to produce essential proteins, like serum albumin, and its ability to produce clotting factors, reflected in prothrombin time (PT) and International Normalized Ratio (INR).

Why it’s done

Liver function tests are often one of the first steps in determining the cause of symptoms like jaundice, fatigue, or abdominal pain. These tests are necessary to identify potential liver disease or damage, especially when symptoms are present.

They help evaluate the severity of diagnosed liver conditions and monitor the progression of diseases like hepatitis or cirrhosis.

Routine blood tests can screen for liver abnormalities, even if symptoms aren’t present. Elevated levels of liver enzymes, such as ALT and AST, can indicate liver inflammation or injury, guiding further diagnostic investigations.

Liver function tests also help assess the impact of medications on liver health, as certain drugs can cause liver toxicity or dysfunction. By monitoring liver health, it’s possible to guarantee safety and prevent further liver damage.

These tests are essential in maintaining overall health and detecting potential liver problems early on.

Who it’s for

Liver function tests (LFTs) are designed for individuals who require an assessment of their liver function. These tests are typically recommended for people experiencing symptoms of liver disease, such as jaundice, abdominal pain, or unexplained fatigue.

Individuals taking medications that could impact liver health may also need LFTs. Those with risk factors like obesity, diabetes, or a history of alcohol use may undergo routine LFTs as part of their annual health check-ups.

LFTs are essential in the following scenarios:

Risks

As one prepares to undergo liver function tests, it’s natural to wonder about the potential risks involved. Minor discomfort, such as soreness or bruising at the blood draw site, is common but usually resolves quickly after the procedure. Serious complications from blood sample collection are infrequent.

To ensure accurate test results, it may be necessary to pause certain medications before testing. Fasting for 10-12 hours beforehand is also often required, allowing the body to stabilize and ensuring that test results reflect actual liver function.

When a blood sample is taken, it’s handled and processed carefully to prevent interfering factors like hemolysis, icterus, or lipemia from affecting the results. Minor complications can occur, but they’re usually transient and resolve quickly.

Understanding and minimizing these risks can help individuals feel more confident when undergoing liver function tests.

How you prepare

Preparing for a liver function test involves several steps to ensure accurate results. Thousands of individuals undergo these tests annually, often as part of routine health checks or to monitor chronic health conditions.

Fasting 10-12 hours before the test is often recommended to prevent certain foods from affecting enzyme levels.

It’s essential to inform about all medications, including over-the-counter drugs and supplements, as some may need to be paused before testing.

Clear instructions about preparation should be followed to avoid any factors that could influence test results.

Routine checkups may include liver function tests as part of thorough metabolic panels.

Medications should only be discontinued with guidance to prevent potential health risks.

What you can expect

A liver function test typically begins with a quick and relatively painless blood draw. The process involves sitting comfortably while a healthcare professional draws a blood sample from a vein in the arm; this takes just a few minutes, and a slight pinch may be felt when the needle is inserted.

To ensure accurate results, fasting for 10-12 hours before the test may be required; this means skipping breakfast and any morning medications that could affect liver function markers. Regular eating and drinking can resume afterward.

The blood sample is sent to a lab for analysis, where it’s tested for various liver enzymes, such as ALT, AST, ALP, bilirubin, and albumin. These tests, collectively known as a liver function panel, provide a snapshot of the liver’s overall health.

Results typically take hours to days to arrive and help determine if the liver is functioning correctly. After the blood draw, normal activities can be resumed unless feelings of lightheadedness occur, in which case resting for a few minutes is recommended.

Results

Liver function test results can be a nerve-wracking experience, especially when there are concerns about liver health.

The results indicate whether the liver is functioning correctly. Understanding what the numbers mean is essential.

Elevated levels of ALT and AST may indicate liver inflammation or damage, which can be a sign of liver disease. High alkaline phosphatase (ALP) levels may suggest a potential bile duct obstruction or cholestatic disease.

Low albumin levels can signal chronic liver disease, as the liver produces this essential protein. Increased bilirubin levels may indicate liver dysfunction or jaundice, which occurs when the liver can’t adequately clear bilirubin from the bloodstream. A prolonged prothrombin time (PT) test can indicate liver disease, reflecting the liver’s compromised ability to produce clotting factors, which can affect blood clotting.

Liver function test results help assess the liver’s health and detect potential liver disease. Understanding these results enables taking the necessary steps to maintain healthy liver function.